The mathematics club at WVWC has meets once a month and discusses a wide variety of topics. Some recent topics have included fractals and mathematics games.

The Hallam Mathematics Honorary was named after William H. Hallam, a Mathematics professor at West Virginia Wesleyan College from 1928-1943. Students are selected for membership during their sophomore year at WVWC. Students that have shown excellent skills in Mathematics are chosen for this academic honorary.

The Putnam Exam is a national mathematics exam given on the first Saturday of January every year. Wesleyan also gives the test on campus and gives a cash prize every Spring to its highest scorer.

The East Central Colleges (ECC) Mathematics contest is a Mathematics contest held every Spring at a member college. Students who participate are split into teams of four and solve problems. The highest scorers are given cash prizes. Recently WVWC had a team that placed second in this competition.